From microscopic haematuria to kidney failure: The hidden progression of IgA nephropathy

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and a leading cause of chronic kidney disease globally. IgAN often presents with varied symptoms, and general practitioners (GPs) play a key role in its early detection and management.

This review aims to provide GPs with an overview of IgAN, focusing on clinical presentations that warrant referral to nephrology and highlighting common pitfalls in primary care management with a case example.

Recognising high-risk features of IgAN through symptoms such as haematuria or proteinuria, addressing modifiable factors and understanding recent advances in management are vital for improving patient outcomes. New therapies targeting pathogenic pathways underscore the importance of collaborative care.