Related Experiment Video
Updated: May 14, 2026

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
Published on: March 24, 2023
Intraoperative integration of nTMS, CCEPs and DCS for language. A glance to the next future?
Camilla Bonaudo1,2, Riccardo Carrai3, Edoardo Pieropan4,5
1Univeristy of Florence, Florence, Italy. camilla.bonaudo@unifi.it.
Background:
Direct-Cortical-Stimulation (DCS), Navigated-Transcranial Magnetic-Stimulation (nTMS), Cortico-Cortical-Evoked-Potentials (CCEPs) can be synergically used to monitor Language-network.
Methods:
We illustrate a case of multimodal approach for removal of one left fronto-temporo-insular Low-Grade-Glioma.
Results:
A 32-years-old female patient was operated in awake surgery (using D080-picture-naming-test). We documented a matching correspondence among frontal nTMS + spots, Penfield DCS, and CCEPs stimulation strip. The same was found in the temporal area among nTMS, DCS, and CCEPs recording strip. [Average distance among nTMS, DCS and CCEPs spots = 5.10 mm, STD = 1.08 mm. Se, PPV and Precision:100%].
Conclusions:
We documented the potential utility of matching synergic technologies to preserve language.
Related Concept Videos
Translation
Translation Produces the Building Blocks of Life
Proteins are called the...
Components of Language
Language and Cognition

