Related Experiment Video
Updated: Jan 16, 2026

Author Spotlight: Development and Application of a Canine IBD Gut-on-a-Chip Model for 3D Intestinal Morphogenesis Studies
Published on: February 9, 2024
Imaging Diagnosis-Intestinal Leiomyositis in a 3-Year-Old Labrador Retriever
Mercedes Cantu1, Eric T Hostnik1, Rebecca Urion1
1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Abstract:
A 3-year-old male neutered Labrador Retriever was originally presented to his primary care veterinarian for a 3-4-week history of hyporexia, a 1-week history of anorexia, and vomiting. There was moderate gastrointestinal (GI) distention with heterogeneous soft tissue luminal material within the small intestine in screening abdominal radiographs. Referral and computed tomography were performed, identifying a severe generalized dilation of the GI tract but no obstructive lesion. Severe functional intestinal ileus without obstruction was diagnosed. The patient underwent laparotomy with full-thickness intestinal surgical biopsies due to presumptive infiltrative enteropathy, yielding a diagnosis of intestinal leiomyositis.

