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Arterial hypertension-attributable mortality in Europe, 2012-2021
Marco Zuin1,2,3, Alberto Mazza4, Alessandro Maloberti5,6
1Department of Translational Medicine, University of Ferrara, Ferrara.
Arterial hypertension (HTN)-attributable mortality in Europe increased from 2012 to 2021, particularly in older adults and Eastern Europe. Significant regional and country-level disparities in HTN mortality persist across the continent.
Area of Science:
- Cardiovascular Epidemiology
- Public Health
- Gerontology
Background:
- Comprehensive assessments of arterial hypertension (HTN)-attributable mortality trends in Europe are limited.
- Understanding these trends is crucial for public health interventions and resource allocation.
Purpose of the Study:
- To evaluate HTN-attributed mortality trends in Europe between 2012 and 2021.
- To examine variations in these trends by age, sex, and European region.
Main Methods:
- Utilized WHO mortality dataset for 2012-2021, extracting heart failure-attributed mortality data.
- Analyzed age-adjusted mortality rates (AAMRs) using joinpoint regression modeling.
- Compared trend differences across demographic and regional groups using parallelism tests.
Main Results:
- Overall AAMR increased by 1.6% annually (P < 0.001), with no significant sex differences.
- Mortality trend increased more in individuals aged 70+ compared to those under 70 (P = 0.007).
- AAMRs increased in Northern and Eastern Europe, plateaued in Western and Southern Europe, with observed country-level disparities.
Conclusions:
- HTN-attributed mortality in Europe showed an increasing trend from 2012 to 2021.
- Significant disparities in mortality rates persist across European regions and individual countries.
- Targeted public health strategies are needed to address these growing disparities.
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