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An International Delphi Consensus About Tumor Rupture During Robotic Partial Nephrectomy (Researching UnPredictable
Riccardo Bertolo1, Alessandro Antonelli1, Axel Bex2,3
1Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Borgo Trento Hospital, Verona, Italy.
Tumor rupture during robotic partial nephrectomy (RAPN) is a rare risk. This consensus study defined rupture, identified risk factors like tumor size, and recommended management to minimize spillage, though oncological impact varies.
Area of Science:
- Urology
- Oncology
- Surgical Innovation
Background:
- Tumor rupture during robot-assisted partial nephrectomy (RAPN) presents oncological risks, including potential malignant cell spread and recurrence.
- Standardized guidelines for managing tumor rupture in RAPN are currently lacking.
- This study addresses the need for consensus on definition, risk factors, and management strategies for tumor rupture during RAPN.
Purpose of the Study:
- To establish a consensus definition for tumor rupture in RAPN.
- To identify key risk factors associated with tumor rupture during RAPN.
- To propose standardized management strategies for tumor rupture to mitigate oncological risks.
Main Methods:
- A modified Delphi method was employed, adhering to the ACcurate COnsensus Reporting Document (ACCORD) checklist.
- A panel of 33 international urological experts participated in a two-phase Delphi survey.
- Consensus was defined as ≥70% agreement, with unresolved issues addressed in an online meeting and subsequent voting rounds.
Main Results:
- Consensus was achieved on definitions and management strategies for tumor rupture in RAPN.
- Identified risk factors include larger tumor size, complexity, and endophytic growth patterns.
- Recommended management involves suctioning rather than grasping cancerous tissue and using an endobag; routine conversion to radical nephrectomy is not advised unless unresectable remnants are present.
- Tumor rupture was not definitively linked to distant metastasis, but its oncological impact depends on rupture extent.
Conclusions:
- This Delphi consensus provides a foundational framework for understanding and managing tumor rupture in RAPN.
- Standardized definitions and uniform management strategies are crucial for future research and clinical practice.
- Empirical validation through prospective clinical studies is warranted to further refine management and assess long-term oncological outcomes.
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