Perioperative Wearable Device Features are associated with Moderate-to-Severe Chronic Pain after Surgery in the "All of Us" Research Program

  • 0Department on Biomedical Data Science, Geisel School of Medicine at Dartmouth.

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Summary

This summary is machine-generated.

Consumer wearable devices can predict chronic postoperative pain. Sleep patterns and activity levels before surgery are key indicators for developing long-term pain after surgical procedures.

Area Of Science

  • Biomedical Engineering
  • Digital Health
  • Pain Medicine

Background

  • Chronic pain affects millions, with surgery being a risk factor for developing persistent pain.
  • Current methods for predicting or managing postoperative pain lack reliable biomarkers.
  • Digital health technologies offer new avenues for identifying digital biomarkers.

Purpose Of The Study

  • To investigate the potential of digital biomarkers from wearable devices for predicting chronic pain after surgery.
  • To leverage data from the "All of Us" Research Program, linking Electronic Health Records (EHR) with Fitbit data.

Main Methods

  • Utilized EHR and Fitbit data from 302 surgical patients, including preoperative and postoperative activity and sleep metrics.
  • Developed predictive models for moderate-to-severe pain 3 months to 5 years post-surgery.
  • Analyzed sleep features, activity levels, and demographic data for predictive accuracy.

Main Results

  • Sleep features demonstrated the strongest predictive performance for chronic postoperative pain (AUC of .722).
  • Lower preoperative step variability and higher preoperative REM sleep variability were associated with increased pain risk.
  • Younger age also correlated with a higher risk of developing chronic pain post-surgery.

Conclusions

  • Digital biomarkers derived from consumer wearables show promise in predicting chronic postoperative pain.
  • Integrating wearable data with EHRs can enhance the understanding and management of postsurgical pain.
  • Further research into digital biomarkers could revolutionize pain prevention and treatment strategies.