Related Experiment Video
Updated: May 12, 2026

10:21
Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
Published on: June 14, 2016
10.6K
Fighting cardiac fibrosis using the chemomechanical method
1Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Mechanobiology in Medicine
|October 3, 2025
Abstract:
Diffuse myocardial fibrosis affects disease severity and outcomes in multiple heart diseases. A recent study in NATURE has shown a chemomechanical method to regulate myocardial stromal cell states to suppress fibrosis in vitro and in vivo, which provides a proof-of-concept therapeutic strategy. This study reviews the proposed chemomechanical method and other recent biotechnologies to fight cardiac fibrosis.

