Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

479
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
479
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.2K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Manifestations and Related Risk Factors of Thrombocyte Abnormalities in HIV-Positive Patients Before and After the Initiation of ART.

Infection and drug resistance·2021
Same author

Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution.

Bioactive materials·2021
Same author

Isolation and Culture of Single Microbial Cells by Laser Ejection Sorting Technology.

Applied and environmental microbiology·2021
Same author

Interface-engineered reduced graphene oxide assembly on nanofiber surface for high performance strain and temperature sensing.

Journal of colloid and interface science·2021
Same author

NiCo<sub>2</sub>S<sub>4</sub>nanosheets decorated on nitrogen-doped hollow carbon nanospheres as advanced electrodes for high-performance asymmetric supercapacitors.

Nanotechnology·2021
Same author

Real-time threshold determination of auditory brainstem responses by cross-correlation analysis.

iScience·2021

Related Experiment Video

Updated: Jan 16, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K

Nomogram for predicting early olfactory dysfunction in obstructive sleep apnea-hypopnea syndrome: a multicenter-based

Qingchun Pan1, Qi Yang1, Jing Huang2

  • 1Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Frontiers in Neurology
|October 3, 2025
PubMed
Summary

This study developed a clinical prediction model to identify obstructive sleep apnea-hypopnea syndrome (OSAHS) patients at high risk for olfactory dysfunction using polysomnography (PSG) and clinical data. The model effectively predicts olfactory dysfunction, aiding early intervention.

Keywords:
nomogramobstructiveolfactory functionsleep apneasleep structure

More Related Videos

A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

9.3K
Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

22.6K

Related Experiment Videos

Last Updated: Jan 16, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K
A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

9.3K
Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

22.6K

Area of Science:

  • Sleep Medicine
  • Neurology
  • Otolaryngology

Background:

  • Obstructive sleep apnea-hypopnea syndrome (OSAHS) is associated with various complications, including olfactory dysfunction.
  • Early identification of patients at risk for olfactory dysfunction in OSAHS is crucial for timely intervention.

Purpose of the Study:

  • To develop and validate a clinical prediction model for olfactory dysfunction in patients with OSAHS.
  • To evaluate the combined predictive value of polysomnography (PSG) parameters and clinical symptoms.

Main Methods:

  • Retrospective analysis of 546 OSAHS patients, divided into training, internal, and external validation sets.
  • Overnight PSG for sleep parameter assessment and Sniffin' Sticks tests for olfactory evaluation.
  • LASSO regression and logistic regression modeling, followed by nomogram construction and ROC analysis.

Main Results:

  • The overall incidence of olfactory dysfunction was 38.64%.
  • Seven independent predictors were identified: gender, age, Apnea-Hypopnea Index (AHI), N3%, REM%, TS90%, and Montreal Cognitive Assessment (MoCA).
  • The model demonstrated strong predictive efficacy (AUC = 0.832) with good calibration and clinical utility.

Conclusions:

  • A prediction model incorporating gender, age, AHI, N3%, REM%, TS90%, and MoCA effectively identifies OSAHS patients at high risk for olfactory dysfunction.
  • This non-invasive tool offers robust discrimination and calibration for early risk stratification and intervention planning.