Related Experiment Video
Updated: Jan 16, 2026

Isolation and Functional Assessment of Human Breast Cancer Stem Cells from Cell and Tissue Samples
Published on: October 2, 2020
[Corrigendum] Quercetin‑3‑methyl ether suppresses human breast cancer stem cell formation by inhibiting the Notch1
Longbin Cao1, Yunxiao Yang1, Ziyu Ye1
1Key Laboratory for Medical Molecular Diagnostics of Guangdong Province, Dongguan, Guangdong 523808, P.R. China.
Abstract:
Subsequently to the publication of the above article, the authors drew to the Editor's attention that, for the MCF‑7 cell invasion assay data shown in Fig. 2C on p. 1630, the '10 µM' data panel had been placed incorrectly, and was a duplication of the data panel shown (correctly) for the '20 µM' experiment. Subsequently, upon performing an independent review of the data published in this paper, the Editorial Office alerted the authors to the fact that, in Fig. 2A, the data shown for the MDA‑MB‑231 / 20 µM quercetin‑3‑methyl ester‑0 h and ‑24 h data panels were strikingly similar, such that these were apparently derived from the same original source, where the results of differently performed experiments were intended to have been portrayed. After re‑examining their original data, the authors realized that these data in Fig. 2C had inadvertently been assembled incorrectly. The revised version of Fig. 2, showing the correct data for the MDA‑MB‑231 / 20 µM quercetin‑3‑methyl ester‑24 h experiment in Fig. 2A and the '10 µM' data panel in Fig. 2C, is shown on on the next page. The authors are grateful to the Editor of International Journal of Molecular Medicine for allowing them this opportunity to publish a Corrigendum, and all the authors agree with its publication. Furthermore, the authors apologize to the readership for any inconvenience caused. [International Journal of Molecular Medicine 42: 1625‑1636, 2018; DOI: 10.3892/ijmm.2018.3741].
Insights
Data errors in cell invasion assays were identified and corrected. This corrigendum revises figures to accurately represent MDA-MB-231 and MCF-7 cell responses to quercetin-3-methyl ester treatments.
Area of Science:
- Molecular Biology
- Cell Biology
- Biochemistry
Related Concept Videos
Inhibition of Cdk Activity
Role Of Notch Signalling In Intestinal Stem Cell Renewal
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not...
PI3K/mTOR/AKT Signaling Pathway

