Related Experiment Video
Updated: May 5, 2026
08:35
Electrotaxis Studies of Lung Cancer Cells using a Multichannel Dual-electric-field Microfluidic Chip
Published on: December 29, 2015
9.1K
Non-cystic fibrosis bronchiectasis in Taiwan
Chia-Ling Chang1,2, Chau-Chyun Sheu3,4, Ping-Huai Wang5
1Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan, Hsinchu, Taiwan.
BMJ Open Respiratory Research
|October 3, 2025
Summary
This study found that while female bronchiectasis patients in Taiwan had more severe imaging results, they experienced better outcomes. Elderly patients over 80 faced a worse prognosis, highlighting age as a critical factor.
Area of Science:
- Pulmonology
- Epidemiology
- Clinical Medicine
Background:
- Bronchiectasis presents diverse etiologies and geographic variations.
- Large-scale data from Southeast Asia are limited.
- Understanding local characteristics is crucial for effective management.
Purpose of the Study:
- To characterize bronchiectasis patients in Taiwan.
- To investigate clinical features, microbial profiles, and treatment patterns.
- To analyze outcomes and identify prognostic factors.
Main Methods:
- A multicentre, retrospective, observational cohort study.
- Data collected from January 2017 to June 2020.
- Included comprehensive clinical data and 1-year follow-ups via electronic forms.
Main Results:
- 2753 patients enrolled; mean age 67; 42% male.
- Common isolates: Pseudomonas aeruginosa (22%), Klebsiella pneumoniae (11%).
- Female patients had worse imaging but better lung function, fewer exacerbations, and lower mortality.
Conclusions:
- Female bronchiectasis patients in Taiwan show better prognosis despite severe imaging.
- Patients over 80 years old have a significantly worse prognosis.
- Age and sex are important prognostic indicators in Taiwanese bronchiectasis patients.
Keywords:
Bronchiectasis
Related Concept Videos
01:23Cystic Fibrosis: Pathogenesis
1.1K
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
1.1K
01:24Cystic Fibrosis: Management
657
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
657
01:28Pulmonary Tuberculosis II
2.5K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.5K
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
3.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
3.4K
01:24Chest Physiotherapy
3.0K
Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
3.0K
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
77
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
77