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Updated: Jan 16, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Pediatric Severe Oropharyngeal Dysphagia: A Clinical Challenge Addressed Through a Novel Approach
Steven Osorio1,2,3, Maria Camila Borbon4, Cheryl Hersh5
1Otolaryngology Pediatric Airway Surgery, Hospital Infantil Napoleón Franco Pareja, Cartagena, Colombia. sosorioa@unicartagena.edu.co.
Insights
This case study details a 2-year-old with severe oropharyngeal dysphagia and aspiration, highlighting feeding difficulties from infancy. It explores potential causes and treatments for persistent swallowing issues in children.
Area of Science:
- Pediatric Gastroenterology
- Speech-Language Pathology
- Clinical Medicine
Background:
- Persistent oropharyngeal dysphagia and recurrent aspiration are significant challenges in pediatric care.
- Feeding difficulties, including coughing, choking, and cyanosis, can manifest from the neonatal period.
Purpose of the Study:
- To present a case of severe pediatric dysphagia with recurrent aspiration.
- To explore potential underlying mechanisms for persistent swallowing dysfunction.
- To consider therapeutic strategies for managing complex feeding issues in a young child.
Main Methods:
- Utilized flexible endoscopic evaluation of swallowing (FEES) to assess pharyngeal function and aspiration.
- Employed videofluoroscopic swallowing studies (VFSS) to visualize the swallowing process and identify aspiration risks.
- Documented clinical presentation and feeding history from infancy.
Main Results:
- FEES revealed mobile vocal folds, pharyngeal pooling, silent aspiration across consistencies, and absent swallow initiation.
- VFSS confirmed ongoing penetration and aspiration, with contrast coating the trachea.
- The severity of dysphagia necessitated gastrostomy placement.
Conclusions:
- Severe oropharyngeal dysphagia in this pediatric case likely involves complex neuromuscular or functional deficits.
- Further investigation into specific mechanisms is crucial for targeted therapeutic interventions.
- Management requires a multidisciplinary approach, potentially including specialized feeding therapies and strategies to mitigate aspiration risks.
Abstract:
We present the case of a 2-year-old male with persistent oropharyngeal dysphagia and recurrent aspiration. Feeding difficulties began in the neonatal period, characterized by coughing, wet cry, choking, and cyanosis during feeds. Multiple hospitalizations followed, and flexible endoscopic evaluation of swallowing (FEES) showed mobile vocal folds and pharyngeal pooling and silent aspiration with various consistencies, alongside absent swallow initiation. Videofluoroscopic swallowing studies (VFSS) demonstrated ongoing penetration and aspiration, with contrast coating both, anterior and posterior tracheal wall during pharyngeal phase, leading to gastrostomy placement. What mechanisms might explain persistent severe dysphagia in this child, and what therapeutic strategies could be considered?
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