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Transitioning Pediatric Liver Transplant Recipients to Adult Transplant Hepatology: A Practical Guide and Future

Rachel W Smith1, Beverly Kosmach-Park2, Nitika Gupta3

  • 1Department of Pediatrics, UPMC Children's Hospital, Pittsburgh, Pennsylvania, USA.

Pediatric Transplantation
|October 4, 2025
PubMed

Insights

Improving pediatric to adult care transition is vital for liver transplant patients. This article offers a flexible pathway for transition clinics and advocates for system-wide changes to enhance patient and graft survival.

Area of Science:

  • Medicine
  • Pediatrics
  • Transplant Surgery

Background:

  • Transitioning care from pediatric to adult providers poses risks, particularly for liver transplant recipients.
  • Close follow-up and adherence to immunosuppressive therapy are crucial for patient and graft survival in this population.

Purpose of the Study:

  • To provide a flexible framework for establishing transition clinics.
  • To advocate for systemic improvements in care transitions within the US healthcare system.

Main Methods:

  • The article outlines a practical pathway for implementing transition clinics.
  • It emphasizes collaboration between pediatric and adult care teams.

Main Results:

  • Existing literature highlights the need for better transition protocols.
  • Specific, actionable steps for clinic implementation and inter-departmental partnerships are currently lacking.

Conclusions:

  • Implementing tailored transition clinics can mitigate risks during care transfer.
  • System-wide changes are necessary to optimize the transition process for improved long-term outcomes in liver transplant patients.

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