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Comparative efficacy of two different subthreshold yellow laser treatments for chronic central serous
O Artunay1, M Ozbek1, S Pehlivanoglu1
1Ophthalmology Department, Beyoglu Eye Training and Research Hospital, Bereketzade Cami Sk. No: 2, 34421 Istanbul, Turkey.
Purpose:
To investigate and compare the anatomic and functional outcomes in patients with chronic central serous chorioretinopathy (cCSC) who have undergone subthreshold laser therapy using either the Navigated Microsecond Laser (nMSL) or Endpoint Management™ (EpM) system.
Methods:
This retrospective study evaluated 80 eyes (78 patients) with cCSC. Patients were divided into two groups: nMSL treatment (n=39, group 1) and the EpM procedure (n=41, group 2). The primary outcomes at 6 months were changes in best-corrected visual acuity (BCVA) and central macular thickness (CMT), along with the rate of complete subretinal fluid (SRF) resolution.
Results:
Group 1 demonstrated a significantly greater improvement in BCVA compared to group 2 at both 3 and 6 months post-treatment (P=0.006 and P=0.013, respectively). Both groups exhibited a statistically significant decrease in mean CMT. At 6 months, a higher proportion of patients in group 1 achieved complete resolution of SRF compared to group 2 (76.9% vs. 61.0%).
Conclusion:
According to our findings, navigated MSL is highly effective in terms of visual outcomes and retinal morphology. EpM is also effective in decreasing SRF in cCSC patients. In cCSC patients, nMSL therapy may be a more effective and safe approach for restoring macular anatomy and visual outcomes than EpM.
