A multinational survey of physician knowledge about management of chronic hepatitis C

Mohamed El-Kassas1, Yusuf Yilmaz2, Chun-Jen Liu3

  • 1Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt; The Global Liver Council, Center for Outcomes Research in Liver Diseases, Washington DC, United States.

Annals of Hepatology
|October 4, 2025
PubMed

Insights

Physicians know hepatitis C virus (HCV) guidelines well but have knowledge gaps. Continuous education is vital for better HCV patient care and adherence to management protocols.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Viral Hepatitis Management

Background:

  • Up-to-date knowledge of hepatitis C virus (HCV) management is crucial for optimal patient outcomes.
  • Physician awareness, attitudes, and barriers to current HCV guidelines impact care.
  • Post-treatment follow-up is essential for managing HCV complications and risks.

Purpose of the Study:

  • Evaluate physicians' awareness and attitudes towards current HCV management guidelines.
  • Assess physician self-efficacy, perceptions, and barriers related to HCV treatment and follow-up.
  • Identify knowledge gaps and areas for improvement in HCV care protocols.

Main Methods:

  • A 48-question survey was distributed to healthcare providers treating HCV patients.
  • The survey assessed practices, guideline familiarity, and attitudes regarding HCV management.
  • 183 physicians from 8 countries completed the survey.

Main Results:

  • Most physicians (95%) were aware of HCV treatment guidelines (EASL 84%, AASLD 72%).
  • 94% believed post-HCV treatment follow-up is effective, and 93% recommended it.
  • Despite high guideline awareness (90%), 39% reported inconsistencies; 86% recognized the need for follow-up after sustained virological response (SVR).

Conclusions:

  • Physicians show strong awareness of HCV guidelines but have potential knowledge gaps and inconsistencies.
  • Continuous education and support are essential for enhancing adherence to HCV management protocols.
  • Effective post-treatment follow-up strategies are recognized, but ongoing education is needed to optimize care.
Abstract

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