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Updated: Jul 27, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Identifying anatomic brain structures using ultra-low field MRI in newborns.
Anne Groteklaes1, Efe Nacarkucuk1, Till Dresbach1
1Department of Neonatology and Pediatric Intensive Care, Children's Hospital University of Bonn, Bonn, Germany.
Portable ultralow-field (ULF) MRI reliably measures neonatal brain structures, correlating well with standard ultrasound. This point-of-care imaging may increase access to magnetic resonance imaging (MRI) for infants.
Area of Science:
- Neonatal imaging
- Medical physics
- Neuroscience
Background:
- Cranial ultrasound is standard for neonates but has limitations.
- Early postnatal MRI offers better measurements but has limited accessibility.
- Portable ultralow-field (ULF) MRI presents a potential solution to expand MRI access.
Purpose of the Study:
- To compare ULF MRI and cranial ultrasound for neonatal brain measurements.
- To assess the reliability of ULF MRI in neonatal neuroimaging.
Main Methods:
- Paired ULF MRI and cranial ultrasound scans were performed on 28 term newborns.
- Dimensions of ten standard anatomic brain structures were measured and compared between modalities.
Main Results:
- A significant correlation was found between ULF MRI and ultrasound biometrics for most brain structures (median correlation coefficient 0.73).
- ULF MRI reliably displays neonatal brain biometry.
Conclusions:
- ULF MRI is a reliable tool for neonatal brain biometry, comparable to ultrasound.
- Point-of-care ULF MRI at the neonatal bedside during natural sleep can potentially increase MRI accessibility.
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