Model to predict postoperative complications after hepatectomy based on comprehensive complication index: A...

Area of Science:

• Hepatobiliary surgery
• Surgical oncology
• Patient safety

Background:

• Hepatectomy patients face complex, multi-system postoperative complications.
• The Comprehensive Complication Index (CCI) offers a standardized method for assessing complication severity.
• Identifying high-risk patients is crucial for targeted preoperative and preventive strategies.

Purpose of the Study:

• To utilize the Comprehensive Complication Index (CCI) for detailed assessment of postoperative complications after hepatectomy.
• To identify key predictors of severe complications and high-risk patient groups.
• To inform and enhance preoperative management and preventive interventions.

Main Methods:

• Retrospective analysis of 1350 hepatectomy cases, evaluating adverse events within 30 days.
• Calculation of CCI scores using the Clavien-Dindo Classification (CDC) system for each complication.
• Statistical analysis to identify independent risk factors and protective factors for severe complications.

Main Results:

• An overall complication rate of 46.61% was observed across 21 recorded complication types.
• High CCI scores correlated with significantly longer hospital stays.
• A predictive nomogram demonstrated strong performance (AUC 0.844), identifying risk factors like prolonged hospital stay and preoperative pulmonary comorbidities.

Conclusions:

• A validated predictive model effectively identifies patients at high risk for severe hepatectomy complications.
• This tool supports perioperative care by guiding preventive measures and early interventions.
• Improved patient outcomes are anticipated through targeted risk stratification and management.