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Updated: Jan 16, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Pharyngeal high-resolution manometry in dysphagia care: clinical experience in a tertiary referral centre
Daniel Saad1, Can Doruk1, Margaret Coffey2,3
1National Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.
Objective:
Pharyngeal high-resolution manometry provides detailed insights into pharyngeal swallowing biomechanics by offering high-resolution pressure measurements across the pharynx and upper oesophageal sphincter. Here we present our early experience using the technology.
Methods:
Retrospective cohort study of 43 patients who underwent pharyngeal high-resolution manometry assessment for dysphagia at a tertiary dysphagia clinic. Swallows of varying consistencies were tested, and key metrics based on international guidelines were analysed.
Results:
PHRM facilitated the diagnosis of cricopharyngeal spasm, pharyngeal weakness and upper oesophageal sphincter dysfunction. It revealed pharyngeal weakness in 50 per cent and ruled out cricopharyngeal spasm in 20 per cent of patients with suspected findings. In post-treatment failures, it detected pharyngeal weakness in 83 per cent of cases. Pharyngeal high-resolution manometry also supported diagnosis and management of retrograde cricopharyngeal dysfunction and globus sensation.
Conclusion:
Pharyngeal high-resolution manometry is a valuable adjunct in evaluating dysphagia, enabling more accurate diagnoses and tailored treatments. It helped avoid unnecessary surgeries and improved care for patients with complex swallowing disorders.
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