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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
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Modular Iminophosphorane as Hydrogen Atom Transfer Catalyst for Selective C(sp3)-H Functionalization

Min Jiang1, Wei Zhang1, Pu-Sheng Wang1

  • 1Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.

Organic Letters
|October 6, 2025
PubMed
Summary

Iminophosphoranes act as tunable hydrogen atom transfer catalysts, overriding typical C(sp3)-H bond preferences. Acridinium photoredox catalysis enables selective C(sp3)-H alkylation, with substituent modulation enhancing regioselectivity.

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