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Updated: May 8, 2026

One-step Metabolomics: Carbohydrates, Organic and Amino Acids Quantified in a Single Procedure

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Published on: June 25, 2010

Estimated waste generation from 1 million basic metabolic panels: a multisite U.S. study.

Seema Khattri Bhandari¹, Kwaku Twum², Erving T Laryea¹

¹Department of Pathology, Microbiology and Immunology, 5718 Vanderbilt University School of Medicine , Nashville, TN, USA.

Clinical Chemistry and Laboratory Medicine

|October 6, 2025

Summary

This summary is machine-generated.

High-throughput clinical chemistry analyzers generate significant solid waste and carbon emissions. A study comparing five systems found the dry chemistry Ortho system produced substantially more waste than wet chemistry platforms, highlighting the need for laboratory sustainability.

Keywords:

CO2e automation plastics sustainability waste

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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

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Published on: November 29, 2024

Area of Science:

Clinical laboratory science
Environmental science
Green chemistry

Background:

Clinical laboratory operations are resource-intensive, consuming electricity and water while generating substantial solid waste.
Understanding the environmental impact of diagnostic testing is crucial for developing sustainable laboratory practices.

Purpose of the Study:

To quantify and compare solid waste generation from one million basic metabolic panels (BMPs) across five major high-throughput chemistry analyzer systems.
To estimate carbon emissions (CO2e) from electricity and water usage for each analyzer system.

Main Methods:

Collected annual vendor purchase data for consumables (reagents, packaging, etc.) from five academic medical centers (Jan 2022-Dec 2022).
Categorized and weighed consumables to estimate solid waste per one million BMPs.
Quantified water and electricity usage, calculating CO2e using standard emission factors.

Main Results:

Performing one million BMPs generated: Abbott (995 kg), Beckman (1,274 kg), Roche (579 kg), Siemens (489 kg) of solid waste. The Ortho dry chemistry system produced 160,593 kg.
Plastic constituted the majority of waste across all platforms.
Annualized CO2e from electricity and water use totaled 69,665 kg CO2e.

Conclusions:

Basic metabolic panel analysis generates considerable solid waste and CO2e across major diagnostic platforms.
There is an urgent need for sustainability strategies in diagnostic laboratories to mitigate their environmental footprint.