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Clinical Prognostic Factors for Overall Survival in Patients Undergoing Radical Radiotherapy for Cervical Cancer
Fangfang Hao1, Nanfeng Xiao1, Meng Wang2
1Department of Obstetrics and Gynecology, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
International Journal of Women'S Health
|October 6, 2025
Summary
A history of miscarriage and FIGO stage independently predict short-term survival in cervical cancer patients receiving radiotherapy. These factors significantly impact 2-year overall survival rates.
Area of Science:
- Gynecology
- Oncology
- Radiotherapy
Background:
- Cervical carcinoma (CC) is a leading female malignancy.
- Patient outcomes are a critical focus in clinical research.
- Understanding short-term survival determinants in CC is essential.
Purpose of the Study:
- To evaluate clinical determinants influencing short-term survival in CC patients.
- To identify prognostic factors for 2-year overall survival (OS) in CC patients undergoing radiotherapy.
Main Methods:
- Retrospective examination of 99 CC patients treated with radical radiotherapy (April 2017-March 2022).
- Clinical outcomes assessed using Kaplan-Meier method and Cox proportional hazards model.
Main Results:
- The 2-year OS rate was 77.8%.
- History of miscarriage and FIGO stage were identified as independent predictors of decreased 2-year OS.
- These factors showed statistically significant impact (P < 0.05).
Conclusions:
- History of miscarriage and FIGO stage are independent predictors of short-term OS in CC patients.
- These findings aid in assessing prognostic indicators for patients undergoing radical chemoradiotherapy.
