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Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
Published on: May 23, 2015
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Improving accuracy in percutaneous lung puncture using thoracic respiratory synchronization and laser angle guidance
Qingjie Yang1, Qingtian Li1, Shenghua Lv1
1Department of Thoracic Surgery, Xiamen Humanity Hospital, Fujian Medical University, Xiamen, China.
Frontiers in Medical Technology
|October 6, 2025
Summary
Matching thoracic respiratory activity during percutaneous lung puncture significantly improves accuracy and reduces complications. This technique, combined with laser guidance, offers a more effective approach for lung nodule procedures.
Area of Science:
- Medical Imaging and Interventional Radiology
- Pulmonary Medicine
- Surgical Techniques
Background:
- Percutaneous lung puncture is crucial for diagnosing pulmonary nodules but faces accuracy challenges.
- Conventional methods may lead to suboptimal outcomes and increased complications.
- Improving precision in minimally invasive lung procedures is an ongoing area of research.
Purpose of the Study:
- To evaluate the effectiveness of matching thoracic respiratory activity and laser guidance in percutaneous lung puncture.
- To compare the accuracy and complication rates of this novel technique against conventional methods.
- To determine the feasibility of enhancing percutaneous lung puncture accuracy.
Main Methods:
- A retrospective case-control study involving 277 patients with pulmonary nodules.
- Patients were divided into three groups: conventional puncture, laser guidance, and thoracic respiratory activity matching (Ram).
- Data on puncture accuracy, CT scans, procedure time, and complications were analyzed.
Main Results:
- The thoracic respiratory activity matching group demonstrated a higher rate of reaching the target on the first puncture (67.05%) compared to the laser group (37.63%) and conventional group (23.96%).
- The Ram group also showed significantly reduced procedure times and fewer required CT scans.
- Complication rates were sequentially lower in the Ram group, though not statistically significant (7.95%).
Conclusions:
- Matching thoracic respiratory activity, particularly with laser guidance, significantly enhances percutaneous lung puncture accuracy.
- This technique reduces the number of interventions and procedure duration, potentially lowering complication risks.
- The straightforward nature of this method warrants further investigation in larger prospective trials.

