Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developing a Model of Health and Supportive Care for People with Silicosis in Australia.

Annals of the American Thoracic Society·2025
Same author

Significance of Inducible Laryngeal Obstruction Phenotypes Identified by Latent Class Analysis.

The journal of allergy and clinical immunology. In practice·2025
Same author

Non-respiratory health risks and mortality associated with fighting bushfires (wildfires): a systematic review.

International archives of occupational and environmental health·2025
Same author

Efficacy and safety of a whole lung lavage program for artificial stone silicosis.

Journal of thoracic disease·2024
Same author

Dupilumab-associated hypereosinophilia in severe asthma.

ERJ open research·2024
Same author

Co-repressors AtSDR4L and DIG1 interact with transcription factor VAL2 and promote Arabidopsis seed-to-seedling transition.

Plant physiology·2024

Related Experiment Video

Updated: Jul 5, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
13:01

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

137.1K

The Case for Autoantibody Screening in Stone Benchtop Workers.

Tiffany Lin1, Jun Keng Khoo1, Ryan Hoy1,2

  • 1Department of Respiratory Medicine Alfred Health Melbourne Australia.

Respirology Case Reports
|October 6, 2025
PubMed
Summary

Occupational silica exposure can lead to silicosis and trigger severe autoimmune diseases. Proactive screening for autoimmune conditions in high-risk workers is crucial for early detection and intervention.

Keywords:
antinuclear antibodyautoimmune diseasesilicasystemic sclerosisvasculitis

More Related Videos

Electrochemiluminescence Assays for Human Islet Autoantibodies
09:15

Electrochemiluminescence Assays for Human Islet Autoantibodies

Published on: March 23, 2018

16.0K
A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases
06:50

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

Published on: May 29, 2020

3.0K

Related Experiment Videos

Last Updated: Jul 5, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
13:01

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

137.1K
Electrochemiluminescence Assays for Human Islet Autoantibodies
09:15

Electrochemiluminescence Assays for Human Islet Autoantibodies

Published on: March 23, 2018

16.0K
A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases
06:50

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

Published on: May 29, 2020

3.0K

Area of Science:

  • Occupational medicine
  • Immunology
  • Pulmonology

Background:

  • Occupational silica exposure is a known cause of silicosis and is increasingly linked to systemic autoimmune diseases.
  • Stone benchtop fabrication involves significant risk of silica dust inhalation.

Purpose of the Study:

  • To report a case of complicated silicosis with progressive autoimmune disease in a stone benchtop fabricator.
  • To emphasize the importance of autoimmune screening in silica-exposed workers.

Main Methods:

  • Case report of a 40-year-old stone benchtop fabricator.
  • Diagnosis of complicated silicosis through a screening program.
  • Monitoring of autoimmune markers and clinical progression over time.

Main Results:

  • The patient presented with asymptomatic silicosis and Raynaud's phenomenon, but with an elevated antinuclear antibody (ANA) titre.
  • Over time, he developed progressive autoimmune disease affecting multiple systems and significant respiratory decline.
  • ANA positivity in asymptomatic individuals may indicate future autoimmune disease.

Conclusions:

  • Silica exposure can potentially trigger severe, multisystem autoimmune disease.
  • Proactive autoimmune screening in high-risk occupational groups is vital.
  • Early detection of autoimmune conditions in silica-exposed workers can mitigate long-term morbidity.