Unmasking the Masked: A Case Report of Atypical Methotrexate Toxicity Leading to Severe Bone Marrow Suppression
Dipesh Karki1, Roshna Shrestha1, Asmi Pandey2
1Internal Medicine, B and C Medical College Teaching Hospital and Research Center, Birtamod, NPL.
Abstract:
Methotrexate (MTX), a cornerstone in the management of rheumatic diseases, can induce severe adverse effects if not monitored meticulously. This report details a rare case of MTX-induced severe bone marrow suppression in a 65-year-old female, highlighting the critical importance of dosing accuracy, especially in the elderly. The patient, diagnosed with rheumatoid arthritis, experienced an acute episode of toxicity due to a dosing error. This case underscores the necessity for stringent monitoring and patient education to prevent similar incidents.
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