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Exploring the relationship between exercise and diabetes risk in a prediabetes population
Chih-Wei Chiang1,2,3, Oswald Ndi Nfor1, Wen-Yu Lu1
1Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
International Journal of Medical Sciences
|October 6, 2025
Summary
Maintaining regular exercise significantly lowers the risk of prediabetes progressing to type 2 diabetes in Taiwanese adults. Consistent physical activity is key for diabetes prevention.
Area of Science:
- Endocrinology
- Public Health
- Epidemiology
Background:
- Prediabetes affects a growing global population, with a significant percentage progressing to type 2 diabetes.
- Identifying factors that influence this progression is crucial for effective public health interventions.
Purpose of the Study:
- To investigate the association between exercise habits and the risk of developing type 2 diabetes in individuals with prediabetes.
- To analyze exercise patterns and their impact on diabetes development within a Taiwanese cohort.
Main Methods:
- Utilized data from 4,958 participants in the Taiwan Biobank (TWB).
- Categorized participants into four exercise groups: no exercise, transition from no exercise to exercise, transition from exercise to no exercise, and regular exercise.
- Employed multiple logistic regression analysis, adjusting for gender, with diabetes development as the primary outcome.
Main Results:
- Individuals maintaining regular exercise showed a significantly lower risk of developing diabetes (OR = 0.755, 95% CI = 0.640-0.892) compared to those with no exercise.
- This protective effect of regular exercise was consistent across both women (OR = 0.752, 95% CI = 0.602-0.940) and men (OR = 0.762, 95% CI = 0.591-0.982).
Conclusions:
- Sustained engagement in regular exercise is a significant protective factor against the progression from prediabetes to type 2 diabetes.
- Promoting consistent exercise habits may be an effective strategy for diabetes prevention in adults with prediabetes.
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