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The Gut Microbiome and Cardiac Arrhythmias

Richard A Vautier1, Elaine M Sumners1, Mohan K Raizada1

  • 1University of Florida, Gainesville.

Federal Practitioner : for the Health Care Professionals of the VA, Dod, and PHS
|October 6, 2025
PubMed

Insights

The gut microbiome influences heart health and cardiac arrhythmias. Understanding these gut-heart axis interactions may lead to new therapies for cardiovascular diseases.

Area of Science:

  • Microbiology
  • Cardiology
  • Human Physiology

Background:

  • The gut microbiome's role in human health is gaining recognition.
  • This review explores pathways linking the gut microbiome to cardiac arrhythmias.

Purpose of the Study:

  • To review current research on the gut microbiome's influence on cardiac arrhythmias.
  • To identify potential therapeutic targets within the gut microbiome for cardiovascular health.

Main Methods:

  • Literature review of recent studies.
  • Analysis of pathways and intermediaries mediating gut-heart interactions.

Main Results:

  • Gut microbial products affect cardiovascular physiology and disease.
  • The gut microbiome plays a role in cardiac arrhythmia development.

Conclusions:

  • Research on the gut microbiome's systemic effects is ongoing.
  • Further investigation may yield novel therapies for cardiovascular conditions and improve patient outcomes.
Abstract

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