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Hemodynamic Alterations After Traumatic Amputation in the Immediate Postoperative Period
Lucas N Canaan1, Morgan Krause2, William Zickler3
1Surgery, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Cureus
|October 6, 2025
Summary
Traumatic amputations can cause acute cardiovascular changes. Above-knee amputations were linked to higher need for continuous renal replacement therapy and blood products, suggesting critical hemodynamic shifts in trauma patients.
Area of Science:
- Trauma Surgery
- Cardiovascular Physiology
- Critical Care Medicine
Background:
- Limited research exists on immediate hemodynamic changes after traumatic amputations.
- No standardized protocols guide critical care for these patients.
- Understanding acute cardiovascular alterations is vital for improving outcomes.
Purpose of the Study:
- To evaluate acute cardiovascular effects in patients with traumatic amputations.
- To identify clinical markers associated with these cardiovascular changes.
- To explore the relationship between cardiovascular alterations, morbidity, and mortality.
Main Methods:
- Retrospective observational study.
- Utilized data from a Level I community trauma center's registry (January 2019 - September 2024).
- Included patients with traumatic amputations, analyzing demographic and clinical data.
Main Results:
- Above-knee amputations (AKA) correlated with increased need for continuous renal replacement therapy (CRRT) and higher blood product transfusion volumes compared to below-knee amputations (BKA).
- Higher Injury Severity Score (ISS) was observed in non-survivors versus survivors.
- Small sample size limited definitive statistical conclusions but indicated notable trends.
Conclusions:
- Findings suggest significant acute cardiovascular impacts following traumatic amputations, particularly AKA.
- Further large-scale or multicenter studies are needed to confirm trends and develop management strategies.
- Investigating targeted interventions for hemodynamic support in traumatic amputation patients is warranted.
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