Related Experiment Video
Updated: Jan 16, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Avacopan in Double-Positive Vasculitis...Why Not Consider It?: A Case Report
Shehab Sayed1, Patricia Torres1, Patricia Purón1
1Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Rapidly progressive glomerulonephritis (RPGN) in double-positive patients has a poor prognosis. Adding avacopan to immunosuppressive therapy improved a patient's kidney function, highlighting its potential in managing this severe kidney disease.
Area of Science:
- Nephrology
- Immunology
- Internal Medicine
Background:
- Antineutrophil cytoplasmic antibody-associated vasculitis and anti-glomerular basement membrane disease can cause rapidly progressive glomerulonephritis (RPGN).
- Dual antibody positivity in RPGN portends a poor prognosis, often leading to end-stage renal disease despite aggressive treatment.
More Related Videos
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Pericarditis I: Introduction
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...

