Comparative Evaluation of the Effect on Enamel Solubility and Remineralizing Potential Following Surface Treatment...

Fluoride Varnishes have incorporated calcium and phosphate in various forms, such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and xylitol-coated calcium and phosphate (CXP).

The aim of this in vitro study was to assess and compare the effect on enamel solubility and remineralizing potential following the application of Embrace^TM Varnish, MI Varnish^TM, and Profluorid Varnish.

For assessing both enamel solubility and remineralization potential, 40 enamel specimens were randomly divided into four groups (n = 10/group) each, according to surface treatment: group I-no treatment (control); group II-Embrace^TM Varnish; group III-MI Varnish^TM; group IV-Profluorid Varnish. The specimens were processed according to the respective experimental protocols. The percentage decrease of surface microhardness (SMH) and surface hardness recovery percentage were calculated. For statistical analysis, a paired sample t-test and an analysis of variance (ANOVA) with Tukey's Post Hoc test were applied.

Embrace^TM Varnish demonstrated the lowest mean percentage decrease of SMH, followed by MI Varnish^TM, Profluorid Varnish, and the control group. MI Varnish^TM demonstrated the highest mean SHR%, followed by Embrace^TM Varnish, Profluorid Varnish and the control group.

Embrace^TM Varnish and MI Varnish^TM demonstrated superior acid resistance and higher remineralizing potential compared to Profluorid Varnish.

Karanth SK, Naidu J. Comparative Evaluation of the Effect on Enamel Solubility and Remineralizing Potential Following Surface Treatment with Fluoride-alone Varnish and Two Fluoride Varnishes Containing Calcium and Phosphate Additives: An In Vitro Study. Int J Clin Pediatr Dent 2025;18(5):553-559.