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Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

983
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
983

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Correction: van Doorn et al. Deriving Motor States and Mobility Metrics from Gamified Augmented Reality Rehabilitation Exercises in People with Parkinson's Disease. <i>Sensors</i> 2025, <i>25</i>, 7172.

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Home-Based Augmented Reality Exercise For People With Parkinson Disease: Qualitative Acceptability Study.

Lotte E S Hardeman1, Esther van Benten1,2, Eva M Hoogendoorn1

  • 1Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

JMIR Rehabilitation and Assistive Technologies
|October 6, 2025
PubMed
Summary

Augmented reality (AR) neurorehabilitation is acceptable for Parkinson disease patients at home. This approach complements physical therapy, with long-term adherence crucial for effectiveness.

Keywords:
Parkinson diseaseacceptabilityaugmented realityhome-based rehabilitationneurorehabilitationphysical therapy

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Area of Science:

  • Neurorehabilitation
  • Digital Therapeutics
  • Augmented Reality

Background:

  • Rising Parkinson disease prevalence necessitates innovative, accessible care.
  • Reality Digital Therapeutics (Reality DTx) offers remotely prescribed AR-based gait and balance exercises for home use.

Purpose of the Study:

  • To explore the acceptability of Reality DTx in people with Parkinson disease at a preimplementation stage.

Main Methods:

  • Qualitative exploratory study using semistructured interviews.
  • 22 participants with Parkinson disease completed 6 weeks of Reality DTx at home.
  • Reflexive thematic analysis informed by critical realism.

Main Results:

  • Interindividual variation in perceived effectiveness and effort.
  • Reality DTx is viewed as a valuable complement to supervised physical therapy.
  • Long-term adherence is crucial, supported by therapist guidance and program flexibility.

Conclusions:

  • Remotely prescribed, gamified AR exercises are acceptable for Parkinson disease patients.
  • Findings inform future Reality DTx development, emphasizing patient perspectives alongside clinician input.