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Updated: Jan 15, 2026
Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
Published on: June 16, 2015
Applications of recombinant type III collagen in tissue engineering
Yuchen Shan1, Ting Wang2, Haiyan Lin3,4
1School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.
None:
Recombinant human type III collagen (rhCol III) is a promising biomaterial for tissue engineering due to its excellent biocompatibility and bioactivity. This review summarizes the structure, development, and applications of rhCol III in bone and soft tissue engineering. Advances in genetic engineering have enabled the production of rhCol III with customizable properties. It plays a key role in promoting tissue repair and regeneration, with significant potential in wound healing, skin repair, and anti-inflammatory responses. However, challenges remain in optimizing its mechanical properties for specific applications. Future research should focus on improving production efficiency and clinical translation while addressing potential host responses.
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