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Pathologic Complete Response to Neoadjuvant Radiation Therapy in a Primary Pancreaticoduodenal High-Grade Sarcoma

Jenna R Rocchetti1, Jeffrey M Farma2, Alessandro Bombonati3

  • 1Radiation Oncology, Fox Chase Cancer Center, Philadelphia, USA.

Cureus
|October 7, 2025
PubMed
Summary

Neoadjuvant radiation therapy (RT) can effectively treat high-grade intra-abdominal sarcomas, enabling complete tumor regression and facilitating surgical resection. This approach offers a promising option for local control in these rare malignancies.

Keywords:
high-grade intraabdominal sarcomapancreaticoduodenal sarcomapathologic complete responseradiation therapysoft tissue sarcoma

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