Unveiling Myoepithelioma: A Case Report and Literature Review of an Uncommon Soft Tissue Tumor

Myoepitheliomas are rare salivary gland tumors, comprising only 1%-1.5% of all cases. We report a unique case of a 69-year-old woman with a painless, slowly enlarging right parotid mass. CT imaging showed an ill-defined, irregular, multilobulated heterogeneous lesion compressing the deep parotid lobe. Fine-needle aspiration cytology suggested a benign spindle cell tumor. The patient underwent superficial parotidectomy, and histopathology confirmed a benign myoepithelioma with spindle and epithelioid cells, along with distinctive fibro-myxoid changes. Immunohistochemistry was positive for p63 and S-100. Postoperative recovery was uneventful, and no recurrence was noted at two-year follow-up. This case highlights the importance of considering myoepithelioma in elderly patients and demonstrates distinct radiological and histological features aiding diagnosis.