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Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes
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Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch

Chungen Li1,2, Xueyi Yang1,3, Kyle A Dickerson4

  • 1Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|October 7, 2025
PubMed
Abstract

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