Cardiovascular risk prediction and influencing predictors identification among Bangladeshi individuals using machine

Md Merajul Islam1, Sujit Kumar1, Md A Salam2

  • 1Department of Statistics, Jatiya Kabi Kazi Nazrul Islam University, Mymensingh, Bangladesh.

Plos One
|October 7, 2025
PubMed

Insights

Machine learning accurately predicts cardiovascular disease (CVD) risk in Bangladesh. Key predictors include age, urban living, wealth, and air conditioning use, enabling targeted prevention strategies.

Area of Science:

  • Public Health
  • Biomedical Informatics
  • Machine Learning in Healthcare

Background:

  • Cardiovascular disease (CVD) is a leading global cause of death, significantly impacting Bangladesh.
  • Predictive modeling using machine learning (ML) offers a promising approach for early CVD detection and risk stratification.
  • Identifying high-risk individuals is crucial for developing targeted public health interventions.

Purpose of the Study:

  • To predict high-risk individuals for CVD in Bangladesh using ML algorithms.
  • To identify key influencing predictors of high CVD risk through association mining.
  • To enhance CVD prediction precision and inform prevention strategies.

Main Methods:

  • Utilized Bangladesh Demographic and Health Survey (BDHS) 2022 data (n=2,221).
  • Employed Boruta-based feature selection to identify significant CVD risk predictors.
  • Applied and evaluated multiple ML models (Logistic Regression, Naïve Bayes, ANN, Random Forest, XGBoost) for prediction.
  • Analyzed influencing predictors using association mining rules.

Main Results:

  • Boruta identified age, residence, marital status, wealth, AC ownership, and BMI as key predictors.
  • Extreme Gradient Boosting (XGB) model demonstrated superior performance (Accuracy: 68.22%, AUC: 0.721).
  • Association rules highlighted older age (≥65), urban residence, richest wealth, AC ownership, and widowhood as significant risk factors.

Conclusions:

  • XGBoost shows strong potential for predicting high CVD risk in the Bangladeshi population.
  • Identified key demographic and socioeconomic factors contributing to CVD risk.
  • Findings facilitate the development of targeted CVD prevention and management strategies.
Abstract