Stop using "former": preterm birth and cardiometabolic risk to future health

Michelle M Kelly1

  • 1Villanova University, M. Louise Fitzpatrick College of Nursing, Villanova, PA, USA. michelle.kelly@villanova.edu.

Pediatric Research
|October 7, 2025
PubMed

Insights

Preterm birth increases the risk of future non-communicable diseases, especially those linked to cardiometabolic risk factors. Early support for families with preterm infants is crucial for mitigating these long-term health risks.

Area of Science:

  • Neonatal health
  • Public health
  • Lifespan health research

Background:

  • Preterm birth is a significant global health concern.
  • Infants born prematurely face elevated risks for long-term health issues.
  • Cardiometabolic risk factors are increasingly recognized in adult populations with a history of preterm birth.

Purpose of the Study:

  • To examine the long-term health implications of preterm birth.
  • To understand the influence of various risk factors on cardiometabolic health in preterm infants.
  • To identify strategies for mitigating future health risks in this population.

Main Methods:

  • Longitudinal cohort studies analyzing health outcomes.
  • Multivariate analysis of social, economic, environmental, and biobehavioral factors.
  • Review of existing literature on preterm birth and non-communicable diseases.

Main Results:

  • Preterm birth is associated with increased incidence of non-communicable diseases throughout life.
  • Complex interactions between multiple risk factors modify the onset and severity of cardiometabolic risk.
  • Early life interventions and support are critical for long-term health trajectories.

Conclusions:

  • Preterm birth poses a lifelong risk for cardiometabolic conditions.
  • Addressing socioeconomic, environmental, and behavioral factors is essential for managing preterm birth risks.
  • Proactive guidance and support for families are vital for promoting the health of preterm infants.
Abstract

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