An image-domain deep-learning denoising technique for accelerated parallel brain MRI: prospective clinical
Laura Onac1, Lorand Dobai1, Andrei Mouraviev1
1Ezra AI Inc, New York, NY 10016, United States.
Radiology Advances
|October 8, 2025
Summary
This study introduces a vendor-agnostic AI method to improve MRI scans. The AI successfully reduces scan time by 29% while maintaining or enhancing image quality, benefiting patients and potentially lowering costs.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Radiology
Background:
- Parallel imaging accelerates MRI scans but can amplify noise and introduce aliasing artifacts.
- High acceleration factors in MRI can compromise image quality.
- Developing methods to mitigate artifacts from accelerated MRI is crucial for clinical applications.
Purpose of the Study:
- To evaluate a vendor-agnostic AI approach for artifact removal in highly accelerated MRI.
- To improve image quality in accelerated MRI scans.
- To reduce MRI scan times without sacrificing diagnostic information.
Main Methods:
- AI model trained on retrospectively degraded accelerated MRI images.
- Evaluation using retrospective and prospective highly accelerated MRI datasets from multiple vendors.
- Qualitative assessment by radiologists and quantitative analysis of noise, contrast, and resolution.
Main Results:
- AI model outputs were rated superior to inputs (P < .001) and comparable or superior to baseline images.
- Quantitative metrics showed improved signal-to-noise and contrast-to-noise ratios (P < .001).
- Average scan time reduction of 29% (19%-41% per sequence) was achieved.
Conclusions:
- The vendor-agnostic AI method effectively reduces MRI scan time.
- Image quality was preserved or enhanced, demonstrating robustness across different vendors and scanners.
- This AI approach offers potential for cost reduction and improved patient experience in MRI.
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