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Updated: Jan 15, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Atomically thin bioelectronics.

Dmitry Kireev¹, Shanmukh Kutagulla², Juyeong Hong³

¹Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA, USA.

Nature Reviews. Materials

|October 8, 2025

Summary

This summary is machine-generated.

Two-dimensional (2D) materials offer unique properties for advanced bioelectronic devices. This perspective explores their use in seamless human-body integration for tissue and organ interfacing, outlining future directions.

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Area of Science:

Materials Science
Bioelectronics
Biomedical Engineering

Background:

Tissue-like bioelectronics enable seamless integration with the human body.
Two-dimensional (2D) materials, like graphene, are ideal for creating ultrathin bioelectronic interfaces.

Purpose of the Study:

To comprehensively review 2D materials for bioelectronics.
To present examples of 2D material-based devices for tissue and organ interfacing.
To provide a future roadmap and identify challenges in the field.

Main Methods:

Review of electrical, optical, environmental, and mechanical properties of 2D materials.
Discussion of existing 2D material-based bioelectronic devices.
Analysis of future development trends and challenges.

Main Results:

2D materials possess properties suitable for bioelectronic applications.
Examples of skintronics and organtronics using 2D materials are presented.
A roadmap for future research and development is outlined.

Conclusions:

2D materials are pivotal for next-generation bioelectronics.
Further research is needed to overcome challenges in 2D material-based bioelectronic development.