Pleomorphic Adenoma in an Immunocompromised Patient

Salivary gland tumors are known for its rarity and almost 30%-40% occur in the minor salivary glands, out of which, pleomorphic adenoma (PA) is rated to be the most common benign salivary gland neoplasm. This term was first termed by Willis and is called so, because of the ability of the cells of this tumor to differentiate into epithelial cells and mesenchymal cells, which gives it an unusual histologic pattern. Literature reports most PAs to be associated with parotid salivary glands and palatal salivary glands, the latter being the most common intraoral site of origin. Interestingly, no case reports have been published of a palatal PA in an immunocompromised individual. We report a unique case of a PA arising on the hard palate of a 54-year-old male human immunodeficiency virus-acquired immunodeficiency syndrome patient.