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Interobserver Variability in Hysterosalpingography Interpretation: Radiologists vs Gynecologists.
Ceyda Karadag1, Cemil Gurses2, Adnan Kabaalioglu3
1Department of Obstetrics and Gynecology, Antalya City Hospital, Antalya, Turkey.
International Journal of Women'S Health
|October 8, 2025
Summary
Interobserver variability in hysterosalpingography (HSG) interpretation is significant, especially between radiologists and gynecologists. Standardized guidelines and AI may improve diagnostic consistency for better patient outcomes.
Area of Science:
- Reproductive medicine
- Radiology
- Gynecology
Background:
- Hysterosalpingography (HSG) is crucial for evaluating female infertility.
- Variability in HSG interpretation can impact patient management and outcomes.
Purpose of the Study:
- To assess interobserver agreement in HSG interpretation among radiologists and gynecologists.
- To identify areas of diagnostic consistency and discrepancy in HSG readings.
Main Methods:
- Prospective, multicenter study involving 12 specialists (6 radiologists, 6 gynecologists).
- Independent review of 100 HSG examinations across 10 diagnostic categories and image quality.
- Statistical analysis using Fleiss' kappa (κ) to measure interobserver agreement.
Main Results:
- Interobserver agreement varied from poor to moderate across most categories.
- Highest agreement observed for tubal occlusion (κ ≈ 0.5), uterine anomalies, and hydrosalpinx.
- Poor agreement (< 0.1) noted for subjective parameters like image quality and additional findings.
Conclusions:
- Significant interobserver variability in HSG interpretation exists, particularly between specialties.
- Structured findings show higher agreement than subjective assessments.
- Standardized reporting, interdisciplinary collaboration, and AI-assisted interpretation are recommended to improve diagnostic consistency.
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