Related Experiment Video

Updated: Jul 6, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

9.5K

Selective IL-2 delivery modulates CD8+ T cells in human HLH and ameliorates disease features in a murine model

Tommaso Marchetti1, Samantha Milanesi1, Diana Tintor1

  • 1Division of Immunology and the Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland; Faculty of Medicine, University of Zürich, Zürich, Switzerland.

The Journal of Allergy and Clinical Immunology
|October 8, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
HLHIL-2T cellcytokine complexescytotoxicity

More Related Videos

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
07:25

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice

Published on: September 25, 2019

7.3K
Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

3.9K

Related Experiment Videos

Last Updated: Jul 6, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

9.5K
Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
07:25

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice

Published on: September 25, 2019

7.3K
Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

3.9K

Related Concept Videos

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...

Articles linked to this work by shared authors, journal, and citation graph.

Low-dose interleukin-2 for the treatment of systemic lupus erythematosus: A systematic review and meta-analysis.

Autoimmunity reviews·2026

Optimizing TREC- and KREC-based newborn screening: Risk-stratified algorithms significantly reduce referrals.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2026

ADA2 genotype and enzyme activity may predict vasculitic or hematologic DADA2 phenotype.

Journal of human immunity·2026

Humoral Immune Abnormalities in Transient Childhood Neutropenia: Insights From a 10-year Cohort Study in a Tertiary Center.

Journal of clinical immunology·2026

Variants in human CD48 lead to impaired T cell immunity and increased inflammation.

The Journal of clinical investigation·2026

Neural circuits encode prior knowledge of temporal statistics.

Nature neuroscience·2026

Mechanistic and Clinical Updates in Chronic Rhinosinusitis: 2023-2025.

The Journal of allergy and clinical immunology·2026

Standardised Human Phenotype Ontology Annotation Enables High Quality Phenotypic Data Capture in a Real-World Common Variable Immunodeficiency Cohort.

The Journal of allergy and clinical immunology·2026

Developments in Mast Cell Research.

The Journal of allergy and clinical immunology·2026

ABACHAI - Safety and efficacy of abatacept (s.c.) in patients with CTLA4 insufficiency or LRBA deficiency, a phase II clinical trial.

The Journal of allergy and clinical immunology·2026

Age-stratified CD19+ B cell reference values in children and adolescents -a systematic review and meta-analysis.

The Journal of allergy and clinical immunology·2026

Exploiting KREC: Time for newborn screening and beyond-proceedings from the First International KREC Consortium Meeting.

The Journal of allergy and clinical immunology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us