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Is Psychiatry Ready for Closed-Loop Invasive Neuromodulation?

Sameer A Sheth1,2, John D Rolston3, Wayne K Goodman2

  • 1Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

JAMA Psychiatry
|October 8, 2025
PubMed
Summary

No abstract available in PubMed .

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Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
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In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...