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Related Experiment Video

Updated: Jan 15, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Optimizing high dimensional data classification with a hybrid AI driven feature selection framework and machine

Amina Salhi¹, Rayan Alshamrani², Ashrf Althbiti²

¹Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.

Scientific Reports

|October 8, 2025

Summary

This summary is machine-generated.

Feature selection (FS) significantly enhances classification accuracy by reducing model complexity and training time. The TMGWO hybrid algorithm demonstrated superior performance in identifying key features and improving classification outcomes.

Keywords:

Curse of dimensionality Dimensionality reduction Feature selection Generalization enhancement Hybrid algorithms Model complexity reduction

Related Experiment Videos

Last Updated: Jan 15, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Area of Science:

Machine Learning
Data Science
Bioinformatics

Background:

Feature selection (FS) is crucial for high-dimensional datasets to improve classification accuracy.
FS minimizes model complexity, reduces training time, and enhances generalization.
The curse of dimensionality necessitates effective feature selection strategies.

Purpose of the Study:

To evaluate and compare various classification algorithms for feature selection.
To introduce and assess novel hybrid algorithms for enhanced feature identification.
To demonstrate the impact of feature selection on classification performance metrics.

Main Methods:

Experiments were conducted on the Wisconsin Breast Cancer Diagnostic, Sonar, and Differentiated Thyroid Cancer datasets.
Evaluated standard classifiers: K-Nearest Neighbors (KNN), Random Forest (RF), Multi-Layer Perceptron (MLP), Logistic Regression (LR), and Support Vector Machines (SVM).
Introduced and tested hybrid algorithms: TMGWO (Two-phase Mutation Grey Wolf Optimization), ISSA (Improved Salp Swarm Algorithm), and BBPSO (Binary Black Particle Swarm Optimization).

Main Results:

The TMGWO hybrid approach achieved superior results in both feature selection and classification accuracy.
Comparative analysis showed significant improvements in accuracy, precision, and recall with FS.
TMGWO outperformed other experimental methods in identifying significant features for classification.

Conclusions:

Hybrid feature selection algorithms, particularly TMGWO, offer significant advantages for classification tasks.
Effective feature selection is vital for improving model performance and avoiding the curse of dimensionality.
The study highlights the importance of advanced FS techniques in machine learning applications.