[Cutaneous metastasis of pleural mesothelioma]

Cutaneous metastasis of pleural mesothelioma is a rare manifestation and poses a diagnostic challenge due to its histopathological heterogeneity. We present a clinical case in which cutaneous metastasis of a known pleural mesothelioma was initially misdiagnosed. The correct diagnosis of cutaneous metastasis of a pleural mesothelioma was only confirmed through detailed immunohistochemical analysis. Precise histological classification is of high clinical relevance, as the therapeutic approach particularly depends on the histological subtype and the patient's Eastern Cooperative Oncology Group (ECOG) performance status. Early and accurate diagnosis, as well as timely initiation of appropriate therapy, are prognostically important.