Related Experiment Video
Updated: Jan 15, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Hospital spending for cancers in Hunan, China during 2017 and 2019
Mengyao Xu1,2, Mengjiao Liu3,2, Liqiu Liao4
1Shanghai Pudong New Area Sunqiao Community Health Service Center, Shanghai, 201210, China.
Insights
Cancer hospitalization costs in Hunan Province were substantial, with lung, colorectal, and breast cancers being the most expensive. Factors like cancer type, patient demographics, and hospital characteristics significantly influenced per-capita spending.
Area of Science:
- Oncology
- Health Economics
- Public Health
Background:
- Cancer represents a significant public health challenge globally and nationally.
- Understanding the economic burden of cancer is crucial for resource allocation and healthcare policy development.
Purpose of the Study:
- To quantify hospitalization spending for various cancers in Hunan Province, China.
- To identify key factors influencing cancer hospitalization costs across different cancer types.
Main Methods:
- A retrospective analysis of 872,309 cancer hospitalization records from Hunan Province (2017-2019).
- Data included demographics, diagnoses, comorbidities, hospital details, costs, length of stay, and payer type.
- Multiple linear regression was used to analyze factors associated with log-transformed per-capita costs.
Main Results:
- Total cancer hospitalization cost reached $2490.36 million, with 64.10% covered by medical insurance.
- Leading cancers by cost included lung, colorectum, liver, lip/oral/pharynx, and stomach in men; and breast, colorectum, cervix, lung, and thyroid in women.
- Cancer site, sex, age, comorbidities, length of stay, and hospital level/location significantly impacted per-capita costs.
Conclusions:
- Cancer imposes a considerable economic burden in Hunan Province.
- Lung, colorectal, breast, liver, and stomach cancers constitute approximately half of the total hospitalization expenditure.
- Cancer site, patient demographics, comorbidities, and hospital characteristics are significant determinants of per-capita hospitalization costs.
Objectives:
To describe the hospitalization spending for cancers in Hunan Province, China, and to investigate the hospitalization cost across diverse cancer classifications.
Methods:
We conducted a retrospective study based on the hospitalization admission data from 2017 to 2019 in Hunan Province. We retrieved information on age, sex, diagnosis, number of comorbidities, level of hospitalization, hospital location, hospital costs, length of stay, and type of payer for eligible participants. Factors for cost (log-transformed) were investigated through multiple linear regression.
Results:
A total of 872,309 records of cancer were hospitalized in Hunan Province during 2017-2019, with a total cost of US$2490.36 million, and 64.10% of the cost was covered by medical insurance. The top five cancers in terms of cost were lung (300.32 million), colorectum ($234.56 million), liver ($126.46 million), lip, oral cavity & pharynx ($102.29 million), and stomach ($98.98 million) cancers in men, were breast ($176.03 million), colorectum ($156.15 million), cervix ($112.68 million), lung ($112.21 million), and thyroid ($56.75 million) cancers in women, respectively. Site of cancer, sex, age, year of hospitalization, number of comorbidities, length of stay, hospital level, and hospital location were significantly associated with the per-capita log-transformed cost.
Conclusion:
The economic burden of cancer was heavy in Hunan, and lung, colorectal, breast, liver, and stomach cancers accounted for half of the total cost. Site of cancer, sex, age, comorbidity, level, and location of hospital were factors for the per-capita cost.
More Related Videos
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against...
Cancer Survival Analysis
Cancer
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

