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Immune Checkpoint Inhibitor-Induced Bullous Pemphigoid: Successful Treatment with Dupilumab while Maintaining
Cristina-Maria Florea1, Laurent Parmentier2, Mohamed Abdou2,3
1Department of Medical Oncology, Sion Hospital, Sion, Switzerland.
Case Reports in Oncology
|October 9, 2025
Summary
Immune checkpoint inhibitors (ICIs) can cause skin reactions like bullous pemphigoid. Dupilumab effectively treated this side effect, allowing continued cancer immunotherapy.
Area of Science:
- Oncology
- Dermatology
- Immunology
Background:
- Immune checkpoint inhibitors (ICIs) are a novel cancer therapy.
- Dermatological toxicities are common immune-related adverse events (irAEs).
- Bullous pemphigoid (BP) is a rare but serious irAE.
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