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Updated: Jan 15, 2026

Establishment of Acute Pontine Infarction in Rats by Electrical Stimulation
Published on: August 27, 2020
Acute pontine infarction inducing REM sleep behavior disorder: a novel case report
1Department of Neurology, Nanjing Gaochun People's Hospital, Nanjing, China.
Abstract:
Rapid eye movement (REM) sleep behavior disorder (RBD) is parasomnia characterized by the loss of physiological muscle atonia during REM sleep, resulting in dream-enacting behaviors that often manifest as complex, violent motor activity. While RBD may occur idiopathically, it is frequently associated with neurodegenerative disorders, particularly α-synucleinopathies such as Parkinson's disease. However, secondary RBD linked to acute cerebrovascular events remains poorly documented. Here, we present a novel case of acute pontine infarction precipitating RBD, highlighting the brainstem's critical role in REM sleep regulation and expanding the spectrum of secondary RBD etiologies. This case report underscores the importance of neuroanatomical localization in evaluating acute-onset RBD, particularly in the context of cerebrovascular pathology.
Insights
Rapid eye movement sleep behavior disorder (RBD) can be caused by stroke. This case report details a patient with acute pontine infarction who developed RBD, highlighting brainstem stroke as a potential cause.
Area of Science:
- Neurology
- Sleep Medicine
- Neuroscience
Background:
- Rapid eye movement sleep behavior disorder (RBD) involves loss of muscle paralysis during REM sleep, leading to enacted dreams.
- RBD is often linked to neurodegenerative diseases like Parkinson's, but secondary causes are less understood.
- Acute cerebrovascular events causing secondary RBD are rarely documented.
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