Minimally Invasive Full-Thickness Resection of a Non-Lifting Adenoma in an Ulcerative Colitis Patient Using OVESCO: A...

Area of Science:

• Gastroenterology
• Endoscopic Surgery

Background:

• Ulcerative colitis (UC) patients have a heightened risk of colorectal cancer, requiring surveillance.
• Submucosal fibrosis in chronic UC makes standard endoscopic resection of non-lifting lesions challenging.

Purpose of the Study:

• To evaluate the efficacy of the OVESCO system for resecting a challenging polyp in a UC patient.
• To present a minimally invasive alternative to colectomy for unresectable lesions in UC.

Main Methods:

• A 76-year-old UC patient with a splenic flexure adenoma, unresectable via endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), was treated.
• The OVESCO full-thickness resection device was utilized for polyp removal.

Main Results:

• The OVESCO system successfully resected the adenoma with clear margins.
• Colectomy was avoided, and the patient's bowel function was preserved.

Conclusions:

• Full-thickness resection devices like OVESCO are effective minimally invasive options for challenging polyps in UC patients.
• This approach avoids major surgery and stoma formation, preserving bowel function.