Sagittal Sinus Thrombosis and Ischemic Cerebrovascular Accident in a Patient With Ulcerative Colitis: A Case Report

Niranjan Kc1, Sandipa Sharma2, Saurav Poudel1

  • 1Department of Internal Medicine Nobel Medical College Teaching Hospital Biratnagar Nepal.

Clinical Case Reports
|October 9, 2025
PubMed

Insights

Cerebral venous thrombosis and stroke are rare but serious complications of Ulcerative colitis. Physicians must remain vigilant for these vascular events to reduce patient morbidity and mortality.

Area of Science:

  • Neurology
  • Gastroenterology
  • Vascular Medicine

Background:

  • Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
  • Extra-intestinal manifestations (EIMs) of UC can impact multiple organ systems.
  • Cerebral venous thrombosis (CVT) and stroke are recognized, albeit rare, EIMs.

Purpose of the Study:

  • To highlight the association between Ulcerative colitis and cerebrovascular events.
  • To emphasize the importance of recognizing CVT and stroke in UC patients.
  • To underscore the potential impact of these thrombotic events on patient outcomes.

Main Methods:

  • This is a conceptual summary, not a research study.
  • Literature review of known associations between UC and thrombotic events.
  • Clinical vigilance and awareness among healthcare providers.

Main Results:

  • Cerebral venous thrombosis and stroke are infrequent complications of Ulcerative colitis.
  • The presence of these thrombotic events significantly elevates the risk of morbidity and mortality in UC patients.
  • Early recognition and management are crucial.

Conclusions:

  • Physicians managing Ulcerative colitis patients must maintain a high index of suspicion for arterial and venous thrombosis.
  • Prompt diagnosis and treatment of cerebrovascular events in UC can mitigate severe outcomes.
  • Vigilance for thrombosis is essential for comprehensive Ulcerative colitis care.

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