Chewing Gum as a Delivery System for Cannabidiol: A Commentary

Area of Science:

• Pharmacology
• Drug Delivery Systems
• Oral Health

Background:

• Cannabidiol (CBD) integration into chewing gum is a novel approach for cannabinoid therapeutics.
• Chewing gum as a delivery system may enhance bioavailability and efficacy via oral mucosa absorption.

Purpose of the Study:

• To explore the potential of cannabinoid-infused chewing gum for various health conditions.
• To highlight therapeutic benefits for oral health, anxiety, and pain management.
• To review advantages of chewing gum for discreet self-medication and rapid effects.

Main Methods:

• Commentary and literature review on cannabinoid-infused chewing gum.
• Exploration of therapeutic properties of cannabinoids (anti-inflammatory, antimicrobial, analgesic, anxiolytic).
• Analysis of chewing gum as a drug delivery vehicle.

Main Results:

• Cannabinoid-infused chewing gum shows potential for managing oral health, anxiety, and pain.
• Therapeutic properties of cannabinoids may be impactful in the oral cavity.
• Chewing gum offers discrete self-medication with potentially rapid onset of effects.

Conclusions:

• Significant research gaps exist regarding absorption, dosing precision, and long-term safety.
• Addressing these challenges will establish cannabinoid-infused chewing gum as a versatile drug delivery system.
• Further clinical research is essential to validate the efficacy and safety of cannabinoid-based chewing gum.