Eyelid Radiotherapy-Treated Basal and Squamous Cell Carcinomas: A Case Series.

Area of Science:

• Oncology
• Radiotherapy
• Ophthalmology

Background:

• Eyelid tumors, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), present unique treatment challenges.
• Surgical excision may be difficult or contraindicated in some patients, particularly the elderly or those with comorbidities.

Purpose of the Study:

• To report the successful application of electron hypofractionated radiotherapy for eyelid BCC and SCC.
• To evaluate the efficacy and tolerability of this treatment modality in elderly patients.

Main Methods:

• Two elderly patients with eyelid BCC and SCC were treated with 10MeV electron beam radiotherapy.
• Treatment was delivered using an ELEKTA linear accelerator.
• Patient outcomes were monitored for lesion response and recurrence.

Main Results:

• Both patients experienced successful lesion regression and resolution following hypofractionated radiotherapy.
• No recurrence was observed at one-year follow-up in either case.
• The treatment was well-tolerated, with no significant adverse events reported.

Conclusions:

• Electron hypofractionated radiotherapy is an effective and well-tolerated treatment for eyelid BCC and SCC.
• It presents a viable alternative to surgery, especially for challenging cases.
• This approach offers a promising option for managing eyelid malignancies in select patient populations.